Baccharis dracunculifolia, the main source of green propolis, exhibits potent antioxidant activity and prevents oxidative mitochondrial damage. PDF | The present study had as its objective to evaluate the antibacterial and antibiotic modulatory activity of the Baccharis dracunculifolia (DC). This study aimed to analyze the insecticidal potential of ethanol extract of Baccharis dracunculifolia DC, on Spodoptera frugiperda Smith, (Noctuidae) and.

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Receive exclusive offers and updates from Oxford Academic. The interaction of amphotericin B with ergosterol has been demonstrated in several studies [ 1232 ].

Only caryophyllene oxide showed differences in the MIC values against Pb18 when the medium was supplemented with ergosterol, which suggested that the compound interacts with ergosterol. The substances were dissolved in perdeuterated solvents containing 0.

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Yeast Extract Peptone Dextrose. Complete assignments of 1H and 13C NMR resonances of oleanolic acid, 18a-oleanolic acid, ursolic acid and their oxo derivatives. We used mixtures of MeOH: In vitro antileishmanial, antiplasmodial and cytotoxic activities of phenolic compounds and triterpenoids from Baccharis dracunculifolia D.

The arrow in 9 shows the depression that occurred in the P. Ursolic acid was active in the cytotoxic assays and showed leishmanicidal activity. Gut microbiome approaches to treat obesity in humans.


In the present study, however, all of the compounds that we tested induced changes to the surface of the cells of P. G nero Baccharis Asteraceae: The hexanic fraction and methyl linolenate were the most active against the isolates of Paracoccidioideswith the Haccharis values ranging from 3.

Baccharis dracunculifolia DC. — The Plant List

Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman. Tamoxifen is bsccharis in the treatment of Leishmania amazonensis dracuncuulifolia in mice. Studies on the constituents of the leaves of Baccharis dracunculifolia Asteraceae and their cytotoxic activity. Essencial oils of Baccharis salicifolia, B. Amphotericin B dracuncukifolia used as the control drug.

Email alerts New issue alert. Paracoccidioidomycosis is a prevalent systemic mycosis in Latin America which requires prolonged treatment with highly toxic antifungals. Baccharis is one of the largest genera of the Asteraceae family, which includes more than species that are primarily distributed in southern and southeastern Brazil, Uruguay, Paraguay, Argentina and Bolivia [ 5 ]. The Pb18 cells were examined by scanning electron microscopy Fig. The experiments were run in duplicate and repeated at least once.

Methyl linolenate has been shown to inhibit the cell division of Saccharomyces cerevisiae [ 24 ], and the present study demonstrated that it was one of the most active substances against the four isolates of P. The treatment of choice is a pentavalent antimony sodium stibogluconate [Pentostam] or meglumine antimoniate [Glucantime]both of which are parenteral drugs that are moderately toxic [ 8 ].


After the unbound dye was washed out, the stained protein was dissolved with 10 mM Tris, and the absorbance was measured at a wavelength of nm.

Baccharis dracunculifolia – Wikipedia

The hexane fraction and the isolated compounds were tested at concentrations ranging from 1. In the present study, the control drug, amphotericin B, also showed increased MIC levels in the presence of exogenous ergosterol.

Proliferative inhibition, cell-cycle dysregulation, dracuncuifolia induction of apoptosis by ursolic acid in human non-small cell lung cancer A cells.

Antifungal properties of plants used in Brazilian traditional medicine against clinically relevant fungal pathogens. Compounds 2, 3 and 4 draunculifolia antifungal activity against four isolates of Paracocci dioides with MIC values ranging from 3. Caryophyllene oxide could be binding to the ergosterol, but additional assays are necessary to evaluate if caryophyllene oxide is binding ergosterols in the cellular membrane of P.

The mass detector was set to scan from 40— atomic mass units at a rate of two scans per second. Antimicrobial effect of farnesol, a Candida dracunculifolja quorum sensing molecule, on Paracoccidioides brasiliensis growth and morphogenesis. Sign In or Create an Account.

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